Programmed cell death or apoptosis is critical for the physiological removal of unwanted cells during development, for tissue homeostasis, and in host defense mechanisms. Clarifying the biochemical mechanisms of apoptosis and stress, a common precursor of apoptosis, is a major goal of current biological research.
PIQOR™ Cell Death Microarray is composed of genes encoding key proteins in apoptosis and stress – like caspases, TNF-receptor family members, BCL-2 family members, and heat shock proteins.
PIQOR Cell Death Microarray is available as a convenient microarray kit or within the scope of Microarray Service. Please see download area for "Further information"
On request - please inquire delivery time. |
| Gene overview |
Human: 500 genes
Mouse: 509 genes
Genes are spotted in quadruplicates.
Apoptosis/inflammation
Caspases, death domain proteins, suppressor of death domain proteins, NFκB metabolism, MAPK kinases, TRAFs, TNF family, TNF receptor family, CARDs, BCL-2 family, ras related family, ras association family (rassf1), death effector domain protein, sphingolipid signaling, IAP-type inhibitors of apoptosis proteins, 14-3-3 proteins, IAP/BIR proteins, etc.
Cell cycle
Cell cycle regulators, p53 pathway, etc.
Cytokine signaling
Cytokines, cytokine receptors, STATs, SOCS, chemokines, toll-like receptors, etc.
DNA repair and metabolism
Oncogenes/tumor suppressor genes
Protein kinases
Published or presumed apoptosis regulators, associated proteins, apoptosis-induced genes, etc.
Stress
Heat shock proteins, DnaJ proteins, etc.
Six housekeeping genes and six controls
ACTA2, CYPA, GAPDH, HPRT, TUBA, TUBB, herring sperm DNA, salt, four artificial control RNAs |
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| Figure 1 |
| PIQOR Cell Death Microarray |
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