| Description |
| Rat Anti-Mouse IgG1 MicroBeads can be used for indirect magnetic labeling and subsequent separation of cells where the primary antibody is of the mouse IgG1 isotype. They can also be used for direct positive selection or depletion of mouse B cells expressing IgG1 on the cell surface. |
| Applications |
| Rat Anti-Mouse IgG1 MicroBeads have been used for the isolation of T cells and T cell subpopulations1, B cell subsets2, rat type I alveolar epithelial cells3, and also for the isolation of rare cells such as subsets of kidney cells4, ovarian carcinoma cells5, or myeloma cells6. The isolation of keratinocytes by depletion of non-keratinocytes has also been performed with Rat Anti-Mouse IgG1 MicroBeads.7 |
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| Figure 1 |
| Kidney cell subsets isolated from human kidney using an anti-Tamm-Horsefall glycoprotein antibody for distal tubulus cells and a CD13 antibody for proximal tubulus cells in combination with Rat Anti-Mouse IgG1 MicroBeads. (Courtesy of Dr. Baer, Frankfurt a.M., Germany.) |
| Kidney cells before MACS® Separation |
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| Purified distal tubulus cells |
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| Purified proximal tubulus cells |
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