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| Overview |
| This antibody is suited for the detection and enumeration of human CD161+ cells by flow cytometry or fluorescence microscopy. |
| Details |
Background information
Clone 191B8 recognizes CD161, a C-type lectin membrane glycoprotein. CD161, also known as NKR-P1A, is expressed as an 80 kDa disulphide-linked homodimer and is found on most NK cells and subsets of T cells. In peripheral blood, CD161 is preferentially expressed on T cells of memory phenotype, but it can also be found on subsets of thymocytes and fetal liver T cells.
CD161 has been implicated in triggering NK-mediated cytotoxicity, contributing to target cell recognition by NK cells. |
| Clone | Isotype |
| 191B8 | Mouse IgG2a |
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| Figure 1 |
| Human PBMCs were stained with CD161 antibodies conjugated to FITC (A), PE (B), APC (C) or Biotin (D). Cells stained with CD161-Biotin were additionally stained with Anti-Biotin-APC. Cells were analyzed by flow cytometry. |
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| B |
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| C |
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| Products |
| CD161-FITC, human |
- for 100 tests (1)
Download datasheet
130-092-907
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| CD161-PE, human |
- for 100 tests (1)
Download datasheet
130-092-677
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| CD161-APC, human |
- for 100 tests (1)
Download datasheet
130-092-678
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| CD161-Biotin, human |
- for 100 tests (2)
Download datasheet
130-092-906
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| CD161 pure, human |
- 100 µg in 1 mL
Download datasheet
130-092-676
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µl. |
| (2) One test corresponds to labeling of up to 107 cells in a total volume of 100 µl. |
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