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| Description |
The CD11b (Mac-1 α; integrin αM chain) antibody reacts with the 170 kDa αM subunit of CD11b/CD18 heterodimer (Mac-1, αMß2 integrin). CD11b functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X.
The monoclonal CD11b antibody recognizes the human, mouse, and non‑human primate CD11b antigen.
In mouse, the CD11b antigen is expressed on monocytes/macrophages and microglia. To a lower extent it is expressed on granulocytes, NK cells, CD5+ B-1 cells, and subsets of dendritic cells. |
| Applications |
| The CD11b antibody can be used to identify and enumerate CD11b+ cells by flow cytometry or fluorescence microscopy. This antibody is suitable for MACS® Control applications. For further details, please refer to the datasheet of the separation reagent. |
| Clone | Isotype |
| M1/70.15.11.5 | Rat IgG2b |
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| Figure 1 |
| Mouse splenocytes were stained with CD11b-PE and analyzed by flow cytometry. |
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| Products |
| CD11b-FITC, human and mouse |
- for 100 tests (1)
Download datasheet
130-081-201
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| CD11b-PE, human and mouse |
- for 100 tests (1)
Download datasheet
130-091-240
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| CD11b-APC, human and mouse |
- for 100 tests (1)
Download datasheet
130-091-241
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 μL. |
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