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| Overview |
CD326 (EpCAM) antibodies are suitable for the identification and enumeration of human EpCAM+ cells, e.g. for the
- analysis of epithelial cells from single-cell suspensions of normal and malignant tissues
- detection of human epithelial cells and carcinoma cells in non-epithelial tissue, for example, in peripheral blood or bone marrow.
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| Details |
Background information
Clone HEA-125 recognizes CD326, also known as human epithelial antigen (HEA), epithelial cell adhesion molecule (EpCAM), or epithelial-specific antigen (ESA) and is involved in cell adhesion. The CD326 antigen is broadly expressed on the basolateral surface of carcinoma and epithelial cells in tissues or on circulating tumor cells, and cancer stem cells, but is not found on melanoma, neuroblastoma, sarcoma, lymphoma, leukemia cells, or normal fibroblasts. |
| Clone | Isotype |
| HEA-125 | Mouse IgG1 |
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| Figure 1 |
| Human PBMCs mixed with cells from a breast cancer cell line (SK-BR-3) were stained with CD326 (EpCAM)-FITC (A), CD326 (EpCAM)-PE (B), CD326 (EpCAM)-APC (C) or CD326 (EpCAM)-VioBlue (D) and analyzed by flow cytometry. |
| A |
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| B |
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| C |
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| D |
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| Products |
| CD326 (EpCAM)-FITC, human |
| For research use only |
- for 100 tests (1)
Download datasheet
130-080-301
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| CD326 (EpCAM)-PE, human |
| For research use only |
- for 100 tests (1)
Download datasheet
130-091-253
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| CD326 (EpCAM)-APC, human |
| For research use only |
- for 100 tests (1)
Download datasheet
130-091-254
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| CD326 (EpCAM)-VioBlue, human |
| For research use only |
- for 100 tests (1)
Download datasheet
130-097-324
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 μL. |
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