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| Overview |
| The CD138 antibody can be used for the detection and enumeration of normal and malignant human plasma cells and for immunophenotyping of malignant hematopoietic cells by flow cytometry. |
| Details |
Background information
The CD138 antibody recognizes the human CD138 antigen, a transmembrane heparan sulfate proteoglycan macromolecule also known as syndecan-1. The CD138 molecule interacts with extracellular matrix proteins, cell surface molecules, and other soluble proteins. It is expressed on normal and malignant human plasma cells and on basolateral surfaces of endothelial cells but not on virgin/naive B cells, memory B cells, T cells, or monocytes. |
| Clone | Isotype |
| B-B4 | Mouse IgG1 |
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| Figure 1 |
| Human PBMCs were stained with CD138-PE and CD19-FITC (A), or CD138-APC and CD19-PE (B). Cells were analyzed by flow cytometry. |
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| Figure 2 |
| A mixture of human PBMCs and cells of the human myeloma cell line U266 was stained with CD138-PE (A) or CD138-VioGreen (B) and analyzed with the MACSQuant Analyzer. |
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| Products |
| CD138-PE, human |
| For research use only |
- for 100 tests (1)
Download datasheet
130-081-301
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| CD138-APC, human |
| For research use only |
- for 100 tests (1)
Download datasheet
130-091-250
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| CD138-VioGreen, human |
| For research use only |
- for 100 tests (1)
Download datasheet
130-096-911
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 μL. |
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| References |
| 1. Barthi et al. (2004) Blood 103: 3175–3184. |
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