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CD158f (KIR2DL5)
Overview
The antibody is suitable for the identification and enumeration of CD158f (KIR2DL5)+ cells by flow cytometry or fluorescence microscopy.
The family of killer immunoglobulin-like receptors (KIR) contributes to the regulation of NK cell–mediated cytotoxicity.
Details
Background information
Clone UP-R1 recognizes CD158f (KIR2DL5), a member of the killer immunoglobulin-like receptor (KIR) family which recognizes subsets of HLA alleles. Expression is found mainly on CD56dimCD16+ natural killer (NK) cells but also on a subset of CD8+ T cells.
KIRs are monomeric receptors possessing high allelic polymorphism, with either 2 or 3 Ig-like extracellular domains.
Clone Isotype
UP-R1mouse IgG1
 
Human PBMCs were stained with CD158f (KIR2DL5)-PE and CD56-APC. Cells were analyzed by flow cytometry using the MACSQuant® Analyzer.
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CD158f (KIR2DL5)-PE, human
- for 100 tests (1)
Download datasheet
130-096-199
Qty.:
 

CD158f (KIR2DL5) pure, human
- 100 µg in 1 mL
Download datasheet
130-096-200
Qty.:
 

(1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µL.
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Mouse IgG1 - isotype control antibodies
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