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| Overview |
The antibody is suitable for the identification and enumeration of CD158f (KIR2DL5)+ cells by flow cytometry or fluorescence microscopy. The family of killer immunoglobulin-like receptors (KIR) contributes to the regulation of NK cell–mediated cytotoxicity. |
| Details |
Background information Clone UP-R1 recognizes CD158f (KIR2DL5), a member of the killer immunoglobulin-like receptor (KIR) family which recognizes subsets of HLA alleles. Expression is found mainly on CD56dimCD16+ natural killer (NK) cells but also on a subset of CD8+ T cells. KIRs are monomeric receptors possessing high allelic polymorphism, with either 2 or 3 Ig-like extracellular domains. |
| Clone | Isotype |
| UP-R1 | mouse IgG1 |
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| Human PBMCs were stained with CD158f (KIR2DL5)-PE and CD56-APC. Cells were analyzed by flow cytometry using the MACSQuant® Analyzer. |
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| Products |
| CD158f (KIR2DL5)-PE, human |
- for 100 tests (1) Download datasheet 130-096-199
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| CD158f (KIR2DL5) pure, human |
- 100 µg in 1 mL Download datasheet 130-096-200
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µL. |
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