Recent developments in neuroscience have been complemented by concomitant advances in stem cell research, especially in the fields of Alzheimer’s and Parkinson's research. Flow cytometry has played a significant role in these developments and is routinely used in the characterization of neural stem cells, progenitors cells and the different functional cell types within the brain.
The MACSQuant Analyzer assays for Neuroscience include:
Neural stem cell and progenitor cell characterization
Identification and characterization of different neurons (Cholinergic, Dopaminergic, etc)
Identification and characterization of astrocytes and glial cells
Monitoring cellular viability, apoptosis and cell cycle
References
Baklaushev, VP et al. Downregulation of gap junctions in astrocytes by monoclonal antibodies against the second extracellular loop of Connexin-43 (2011) Br J Medicine Medical Res.
Dos Santos, Cet al. Anti-tumorgenic effects of a mutant of the heparin affin regulatory peptide (HARP) on the U87 MG glioblastoma cell line (2010) Int. J. Cancer.
Jungblut, M et al. Isolation and characterization of living primary astrglial cells using the new GLAST-specific monoclonal antibody ACSA-1 (2012) Glia.
Vlashi, E et al. Metabolic state of glioma stem cells and nontumorigenic cells (2011) PNAS.
