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| GadoSpin™ MRI agents - from structure to pharmacology |
GadoSpin™ and FeraSpin™ contrast agents make up the first and only portfolio tailored for pre-clinical MRI.
Our product range includes agents that have been designed specifically for indications such as oncology, inflammatory and cardiovascular disease:
GadoSpin M is our all-purpose extracellular gadolinium chelate agent for classical contrast-enhanced MRI and for studying CNS disease. The trusted standard from human clinical MRI has been formulated for small animal imaging.
GadoSpin P is a long-circulating imaging agent for magnetic resonance angiography (MRA). It is based on a high-molecular-weight polymer that does not extravasate from intact blood vessels.
GadoSpin D is a unique dendritic MRI agent for studying blood vessel integrity and angiogenesis in tumors and inflamed tissue via dynamic contrast-enhanced (DCE) MRI. It contains 24 gadolinium ions in a perfectly globular structure.
GadoSpin F is a unique MRI agent specific for atherosclerosis. It contains a hydrophobic targeting moiety for high protein binding affinity. The agent accumulates in atherosclerotic plaques and enables direct T1-weighted visualization of plaque burden. |
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| GadoSpin™ D, MRI contrast agent |
| Product | Applications | order no. |
| GadoSpin D | Small animal MRI of vasculature and dynamic contrast-enhanced (DCE) MRI | 130-095-164
130-095-165 |
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| GadoSpin™ F, MRI contrast agent |
| Product | Applications | order no. |
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| GadoSpin F | Small animal MRI of atherosclerosis and MR angiography | 130-095-162
130-095-163 |
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| GadoSpin™ P, MRI contrast agent |
| Product | Applications | order no. |
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| GadoSpin P | Small animal MRI angiography | 130-095-136
130-095-137 |
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| GadoSpin™ M, MRI contrast agent |
| Product | Applications | order no. |
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| GadoSpin M | Small animal MRI of the extracellular space | 130-095-134
130-095-135 |
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