|
|
 |
|
miRXplore platform
|
|
|
microRNA Expression Profiling Service – specificity down to a single nucleotide
We developed our miRXplore Microarray Platform together with leading scientists (Landgraf & Tuschl et al.; 2007; Cell) for analysis of microRNA where specificity is an issue.
This microarray platform sets a benchmark in terms of specificity in microarray-based microRNA profiling analysis. With the miRXplore Microarray Service even the discrimination of closely related microRNAs with just a single nucleotide exchange is possible.
The miRXplore Universal Reference (UR), a synthetic microRNA pool, has been developed for the comparison of multiple samples. Samples and controls are hybridized and compared to the miRXplore Universal Reference, on individual miRXplore Microarrays. Subsequently, re-ratios can be calculated to compare samples versus control. This method saves much of your valuable starting material.
The miRXplore Universal Reference also enables global, absolute quantification of microRNAs (Bissels & Tuschl et al.; 2009; RNA). The defined microRNA concentration in the miRXplore Universal Reference allows determination of the absolute microRNA concentration in your sample by translating the respective signal intensities.
For more information on our miRXplore Microarray Platform, please refer to the attached PDF.
Additional details on the miRXplore Universal reference can also be downloaded here.
|
|
|
|
|
© 1999 - 2012 Miltenyi Biotec ¦ Terms & conditions ¦ Legal notes
|
